Construct monitoring boundaries

Functions to compute rejection boundaries

get.boundaries.design()

Get Pocock or OBF-style boundaries at the design stage

get.boundaries.aspend()

Derive boundaries with alpha-spending.

Get adjusted p-values

Functions to compute adjusted p-values

get.pvalue.sw()

Get a stage-wise p-value after the trial is complete.

Alpha-spending

Alpha-spending functions

pocock.spend()

Pocock approximation, alpha spending function

obf.spend()

O'Brien-Fleming approximation, alpha spending function