Data generation function from covariate adjusted log-rank paper

Data generation function from covariate adjusted log-rank paper

data_gen2(
  n,
  theta,
  randomization,
  p_trt,
  case = c("case1", "case2", "case3", "case4"),
  blocksize = 4
)

Arguments

n

total number of subjects to be generated

theta

true treatment effect

randomization

randomization method in c("SR","CABC","permuted_block","minimization","urn")

p_trt

proportion of treatment arm

case

simulation case in the paper

blocksize

block size for permuted block design

Value

A data frame with the following columns:

t

event time

delta

event indicator

I1

assignment to treatment group 1

I0

assignment to treatment group 0

model_w3

covariates

car_strata1, ...

strata variables